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Everyone hates spam.
Some checks evaluate the content - or lack thereof - of an email for signs of spam, but the the sender’s reputation of the email’s source typically plays a greater role in the analysis from an Internet Service Provider’s perspective.
Reputation is a reason permission is so important:
Keep in mind that valid email addresses can:
Professional email marketing services and tools remove such undeliverable addresses automatically. They also take care of technical requirements that can affect sender reputation.
Getting emails delivered is obviously important, but so is knowing when to actually send them out.
Unfortunately, there is no universal recommendation. A good question to ask is when are your readers most likely to open and act on the email? Most marketers combine an understanding of their particular audience and email content with testing to find the answer that works best for their situation.